منابع مشابه
Multifunctional Cinnamic Acid Derivatives.
Our research to discover potential new multitarget agents led to the synthesis of 10 novel derivatives of cinnamic acids and propranolol, atenolol, 1-adamantanol, naphth-1-ol, and (benzylamino) ethan-1-ol. The synthesized molecules were evaluated as trypsin, lipoxygenase and lipid peroxidation inhibitors and for their cytotoxicity. Compound 2b derived from phenoxyphenyl cinnamic acid and propra...
متن کاملNaturally Occurring Cinnamic Acid Sugar Ester Derivatives.
Cinnamic acid sugar ester derivatives (CASEDs) are a class of natural product with one or several phenylacrylic moieties linked with the non-anomeric carbon of a glycosyl skeleton part through ester bonds. Their notable anti-depressant and brains protective activities have made them a topic of great interest over the past several decades. In particular the compound 3',6-disinapoylsucrose, the i...
متن کاملCinnamic Derivatives in Tuberculosis
Tuberculosis (TB) is a threat to worldwide public health, mainly caused by Mycobacterium tuberculosis (M.tb.) bacteria species. Despite the availability of effective treatment, tuberculosis is responsible for more than three million deaths annually worldwide. The high susceptibility of human immunodeficiency virus-infected persons to the disease (Nunn et al., 2005), the emergence of multi-drug-...
متن کاملCinnamic acid derivatives: A new chapter of various pharmacological activities
Cinnamic acid derivatives (CADs) are naturally occurring substances found in fruits, vegetables, flowers and are consumed as dietary phenolic compounds. These play a vital role in the formation of commercially important intermediate molecules which are necessary for the production of different pharmaceutical ingradients. In the present review, cinnamic acid and its derivatives are studied for i...
متن کاملCinnamic Acid and Its Derivatives Inhibit Fructose-Mediated Protein Glycation
Cinnamic acid and its derivatives have shown a variety of pharmacologic properties. However, little is known about the antiglycation properties of cinnamic acid and its derivatives. The present study sought to characterize the protein glycation inhibitory activity of cinnamic acid and its derivatives in a bovine serum albumin (BSA)/fructose system. The results demonstrated that cinnamic acid an...
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ژورنال
عنوان ژورنال: Molecules
سال: 2017
ISSN: 1420-3049
DOI: 10.3390/molecules22081247